TAMIS stands for TransAnal Minimally Invasive Surgery. TAMIS was pioneered in 2009 as a hybrid technique for trans-anal resection of appropriately selected rectal lesions, such as polyps, carcinoid tumors, and under some circumstances, early rectal cancers. It was initially developed by using a single access port designed for abdominal laparoscopic surgery and placing it into the anal canal. By gently filling the rectum with air, the surgeon is able to navigate higher up into the rectum to remove rectal lesions that previously would have required a major abdominal operation. Because of improved visualization and instrumentation with this technique, our ability to remove rectal lesions effectively, completely and safely, has been dramatically improved.